At Perch Fertility, we offer embryo genetic testing, or preimplantation genetic testing (PGT), to screen embryos for genetic abnormalities before implantation. Embryo genetic testing is a valuable tool for couples undergoing In Vitro Fertilization (IVF) and can also help detect known diseases that run in families.

There are many different types of PGT that are commercially available to patients. The most common type, Preimplantation genetic testing for Aneuploidy (PGT-A) can help reduce miscarriage risk and improve the likelihood of a successful pregnancy.

By identifying issues early, we can focus on selecting the most viable and competent embryos for transfer, enhancing your chances of building a healthy family. PGT allows us to analyze the genetic makeup of embryos before transfer and can even identify the sex of an embryo prior to transfer into the uterus.

As the name suggests, PGT is a specialized technique used in conjunction with IVF to assess the genetic makeup of embryos before implantation takes place. The information it reveals is especially valuable for couples at risk of passing on genetic conditions to the baby or those facing recurrent pregnancy loss.

Preimplantation Genetic Testing for Aneuploidy (PGT-A), the most common form of PGT, is a highly advanced method for analyzing embryos during IVF to detect chromosomal abnormalities like aneuploidy.

Aneuploidy occurs when an embryo has too many or too few chromosomes, leading to failed implantation or early miscarriage. Aneuploidy is the most common genetic reason embryos fail to implant and also the most common genetic cause of first-trimester miscarriage.

PGT-A allows us to identify these chromosomal issues with a high degree of accuracy, offering peace of mind to those pursuing IVF. Knowing which embryos have the correct number of chromosomes can give your fertility treatment a better chance of success.

While genetic testing can benefit most patients undergoing IVF, it is especially recommended for:

• Women over 35, where the risk of chromosomal abnormalities is higher.
• Couples with recurrent pregnancy loss.
• Those with a history of failed IVF cycles.
• Individuals interested in family balancing or gender selection.

In addition to the PGT-A test which focuses on detecting the number of chromosomes, other types of embryo genetic testing can include:

• PGT-M (Preimplantation Genetic Testing for Monogenic Disorders): It screens for specific inherited genetic diseases like cystic fibrosis.
• PGT-SR (Preimplantation Genetic Testing for Structural Rearrangements): It identifies structural chromosomal abnormalities, such as balanced translocations.
• PGT-P (Preimplantation Genetic Testing for Polygenic Traits): It assesses embryos for multiple genetic variants associated with certain traits or conditions, such as the risk of heart disease, diabetes, or certain cancers.

The embryo genetic testing process involves the following steps.

• Egg Retrieval & Fertilization: Eggs are retrieved from the ovaries during the IVF cycle and fertilized with sperm in a laboratory. We monitor the fertilization process closely to ensure that the embryos develop normally. 
• Embryo Biopsy: Once the embryo reaches the blastocyst stage, a small number of cells are removed from the outside of the embryo for genetic analysis. This does not harm the embryo and allows us to identify any genetic issues. 
• Genetic Analysis: The biopsied cells are analyzed to identify chromosomal abnormalities. Results are typically available within 2 weeks.
• Embryo Transfer: Once a healthy and normal embryo is identified, it can be transferred into the uterus. 

Research shows that genetic testing can significantly improve implantation rates, reduce miscarriage risk, and enhance overall success in IVF cycles. The controlled, personalized approach at Perch Fertility ensures that each step of the testing process is optimized for your unique needs.

Embryo genetic testing can increase your chances of success and reduce the emotional and financial burden associated with infertility. The IVF cycle is a complex and demanding process, but it can offer hope and possibility for couples struggling with infertility. At Perch Fertility, we are committed to providing personalized care and support throughout your IVF journey.

Our experienced team will guide you through each step of the process, ensuring that you have the best possible chance of achieving pregnancy.

To schedule a consultation with our fertility specialist, please call us at 201-775-0003 or request an appointment online. We are here to answer your questions and provide you with the information and support you need.